Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies.

Staquicini, Fernanda I

Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies. [electronic resource] - Cancer gene therapy 05 2020 - 301-310 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5500

10.1038/s41417-019-0101-2 doi


Animals
Antineoplastic Agents--administration & dosage
Bacteriophages--genetics
Brain Neoplasms--blood supply
Cell Line, Tumor
Dependovirus--genetics
Drug Delivery Systems--methods
Endothelium, Vascular--drug effects
Female
Ganciclovir--administration & dosage
Gene Transfer Techniques
Genes, Transgenic, Suicide--genetics
Genetic Vectors--administration & dosage
Glioblastoma--blood supply
Humans
Mice
Molecular Imaging--methods
Molecular Targeted Therapy--methods
Simplexvirus--genetics
Thymidine Kinase--genetics
Tumor Necrosis Factor-alpha--genetics
Viral Proteins--genetics
Xenograft Model Antitumor Assays