Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.
Prajapati, Sabin
Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. [electronic resource] - Structure (London, England : 1993) 07 2019 - 1124-1136.e4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-4186
10.1016/j.str.2019.04.009 doi
Acetyl Coenzyme A--chemistry
Catalytic Domain
Cloning, Molecular
Coenzyme A--chemistry
Cryoelectron Microscopy
Escherichia coli--genetics
Gene Expression
Genetic Vectors--chemistry
Humans
Kinetics
Models, Molecular
Protein Binding
Protein Conformation, alpha-Helical
Protein Conformation, beta-Strand
Protein Interaction Domains and Motifs
Protein Multimerization
Protein Subunits--chemistry
Pyruvate Dehydrogenase Complex--chemistry
Recombinant Proteins--chemistry
Substrate Specificity
Thermodynamics
Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. [electronic resource] - Structure (London, England : 1993) 07 2019 - 1124-1136.e4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-4186
10.1016/j.str.2019.04.009 doi
Acetyl Coenzyme A--chemistry
Catalytic Domain
Cloning, Molecular
Coenzyme A--chemistry
Cryoelectron Microscopy
Escherichia coli--genetics
Gene Expression
Genetic Vectors--chemistry
Humans
Kinetics
Models, Molecular
Protein Binding
Protein Conformation, alpha-Helical
Protein Conformation, beta-Strand
Protein Interaction Domains and Motifs
Protein Multimerization
Protein Subunits--chemistry
Pyruvate Dehydrogenase Complex--chemistry
Recombinant Proteins--chemistry
Substrate Specificity
Thermodynamics