Euphorbia factor L2 inhibits TGF-β-induced cell growth and migration of hepatocellular carcinoma through AKT/STAT3.
Fan, Lu
Euphorbia factor L2 inhibits TGF-β-induced cell growth and migration of hepatocellular carcinoma through AKT/STAT3. [electronic resource] - Phytomedicine : international journal of phytotherapy and phytopharmacology Sep 2019 - 152931 p. digital
Publication Type: Journal Article
1618-095X
10.1016/j.phymed.2019.152931 doi
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Benzoates--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Movement--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Epithelial-Mesenchymal Transition--drug effects
Euphorbia--chemistry
Fused-Ring Compounds--pharmacology
Hep G2 Cells
Humans
Liver Neoplasms--drug therapy
Macrocyclic Compounds--pharmacology
Male
Mice, Inbred BALB C
Polycyclic Compounds--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
STAT3 Transcription Factor--metabolism
Transforming Growth Factor beta--metabolism
Euphorbia factor L2 inhibits TGF-β-induced cell growth and migration of hepatocellular carcinoma through AKT/STAT3. [electronic resource] - Phytomedicine : international journal of phytotherapy and phytopharmacology Sep 2019 - 152931 p. digital
Publication Type: Journal Article
1618-095X
10.1016/j.phymed.2019.152931 doi
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Benzoates--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Movement--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Epithelial-Mesenchymal Transition--drug effects
Euphorbia--chemistry
Fused-Ring Compounds--pharmacology
Hep G2 Cells
Humans
Liver Neoplasms--drug therapy
Macrocyclic Compounds--pharmacology
Male
Mice, Inbred BALB C
Polycyclic Compounds--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
STAT3 Transcription Factor--metabolism
Transforming Growth Factor beta--metabolism