Suppression of WNK1-SPAK/OSR1 Attenuates Bone Cancer Pain by Regulating NKCC1 and KCC2.

Gao, Jian-Ling

Suppression of WNK1-SPAK/OSR1 Attenuates Bone Cancer Pain by Regulating NKCC1 and KCC2. [electronic resource] - The journal of pain 12 2019 - 1416-1428 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-8447

10.1016/j.jpain.2019.05.005 doi


Animals
Bone Neoplasms--metabolism
Cancer Pain--metabolism
Female
Ganglia, Spinal--metabolism
Gene Expression Regulation--physiology
Protein Kinases--metabolism
Protein Serine-Threonine Kinases--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction--physiology
Solute Carrier Family 12, Member 2--metabolism
Spinal Cord Dorsal Horn--metabolism
Symporters--metabolism
WNK Lysine-Deficient Protein Kinase 1--metabolism
K Cl- Cotransporters