The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells.

Tian, Weihua

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells. [electronic resource] - Nature communications 04 2019 - 1785 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-1723

10.1038/s41467-019-09809-3 doi


Animals
CHO Cells
Cricetinae
Cricetulus
Disease Models, Animal
Fabry Disease--drug therapy
Glycosylation
Lysosomes--enzymology
Male
Mice
Mice, Knockout
Recombinant Proteins--therapeutic use
alpha-Galactosidase--therapeutic use