miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.

Sengupta, Dipta

miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability. [electronic resource] - Gene Jul 2019 - 22-35 p. digital

Publication Type: Journal Article

1879-0038

10.1016/j.gene.2019.04.046 doi


3' Untranslated Regions
Caveolin 1--genetics
Cell Line, Tumor
Cell Proliferation
Cell Survival
Chromatin--metabolism
Down-Regulation
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Histone-Lysine N-Methyltransferase--genetics
Histones--metabolism
Humans
Male
Methylation
MicroRNAs--genetics
Myeloid-Lymphoid Leukemia Protein--genetics
Prostatic Neoplasms--genetics