Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.
Molinaro, Angela
Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS. [electronic resource] - Cell metabolism 06 2019 - 1400-1409.e5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-7420
10.1016/j.cmet.2019.03.010 doi
Animals
Cells, Cultured
HEK293 Cells
Hepatocytes--drug effects
Humans
Insulin--metabolism
Isoenzymes--metabolism
Male
Mice
Mice, 129 Strain
Mice, Inbred C57BL
Mice, Transgenic
Phosphatidylinositol 3-Kinases--genetics
Phosphoinositide-3 Kinase Inhibitors--pharmacology
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
ras Proteins--genetics
Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS. [electronic resource] - Cell metabolism 06 2019 - 1400-1409.e5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-7420
10.1016/j.cmet.2019.03.010 doi
Animals
Cells, Cultured
HEK293 Cells
Hepatocytes--drug effects
Humans
Insulin--metabolism
Isoenzymes--metabolism
Male
Mice
Mice, 129 Strain
Mice, Inbred C57BL
Mice, Transgenic
Phosphatidylinositol 3-Kinases--genetics
Phosphoinositide-3 Kinase Inhibitors--pharmacology
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
ras Proteins--genetics