Compound α-keto acid tablet supplementation alleviates chronic kidney disease progression via inhibition of the NF-kB and MAPK pathways.

Wang, Meng

Compound α-keto acid tablet supplementation alleviates chronic kidney disease progression via inhibition of the NF-kB and MAPK pathways. [electronic resource] - Journal of translational medicine 04 2019 - 122 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1479-5876

10.1186/s12967-019-1856-9 doi


Animals
Apoptosis--drug effects
Diet, Protein-Restricted
Dietary Supplements
Disease Progression
Female
Humans
Inflammation--pathology
Keto Acids--pharmacology
MAP Kinase Signaling System--drug effects
Male
Mice, Inbred C57BL
Middle Aged
NF-kappa B--metabolism
Probability
Renal Insufficiency, Chronic--drug therapy
Reperfusion Injury--complications
Survival Analysis
Tablets