Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia.

Schittenhelm, Marcus Matthias

Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia. [electronic resource] - EBioMedicine Apr 2019 - 340-351 p. digital

Publication Type: Journal Article

2352-3964

10.1016/j.ebiom.2019.03.028 doi


Alternative Splicing
Apoptosis Regulatory Proteins--genetics
Cell Line, Tumor
Cytogenetics
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Humans
Leukemia, Myeloid, Acute--genetics
Neoplastic Stem Cells--metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma--genetics
Protein Biosynthesis
Protein Isoforms--genetics
Stress, Physiological--genetics
Tumor Suppressor Protein p53--genetics