A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma.

van Groningen, Tim

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma. [electronic resource] - Nature communications 04 2019 - 1530 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-1723

10.1038/s41467-019-09470-w doi


Adrenergic Neurons--metabolism
Cell Line, Tumor
Cellular Reprogramming--genetics
Epigenesis, Genetic
Feedback, Physiological
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Mesenchymal Stem Cells--metabolism
Neuroblastoma--metabolism
Receptor, Notch3--genetics