Discovery of novel bacterial FabH inhibitors (Pyrazol-Benzimidazole amide derivatives): Design, synthesis, bioassay, molecular docking and crystal structure determination.

Wang, Yan-Ting

Discovery of novel bacterial FabH inhibitors (Pyrazol-Benzimidazole amide derivatives): Design, synthesis, bioassay, molecular docking and crystal structure determination. [electronic resource] - European journal of medicinal chemistry Jun 2019 - 209-220 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2019.03.026 doi


Bacillus subtilis--enzymology
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Escherichia coli--enzymology
Fatty Acid Synthase, Type II--antagonists & inhibitors
Molecular Docking Simulation
Molecular Structure
Pseudomonas aeruginosa--enzymology
Staphylococcus aureus--enzymology
Structure-Activity Relationship