A novel ex vivo tumor system identifies Src-mediated invasion and metastasis in mesenchymal tumor cells in non-small cell lung cancer.

Padhye, Aparna

A novel ex vivo tumor system identifies Src-mediated invasion and metastasis in mesenchymal tumor cells in non-small cell lung cancer. [electronic resource] - Scientific reports 03 2019 - 4819 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-019-41301-2 doi


Animals
Carcinoma, Non-Small-Cell Lung--genetics
Cell Culture Techniques
Cell Line, Tumor
Epithelial-Mesenchymal Transition--genetics
Extracellular Matrix--genetics
Gene Expression Regulation, Neoplastic--genetics
Genes, src--genetics
Humans
Lung Neoplasms--genetics
Mice
Neoplasm Invasiveness--genetics
Neoplasm Metastasis--genetics
Rats
Signal Transduction--genetics
Spheroids, Cellular--pathology
Tumor Microenvironment--genetics