Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study.
Sansom, Geraud N
Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study. [electronic resource] - Bioorganic & medicinal chemistry letters 05 2019 - 1215-1219 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2019.03.015 doi
Alcohols--chemistry
Amines--chemistry
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation
Cytotoxins--chemistry
Drug Screening Assays, Antitumor--methods
Floxuridine--chemistry
Humans
Indoles--chemistry
Molecular Structure
Prodrugs--chemical synthesis
Proof of Concept Study
Protein Kinase Inhibitors--chemical synthesis
Pyrroles--chemistry
Structure-Activity Relationship
Tumor Hypoxia
Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study. [electronic resource] - Bioorganic & medicinal chemistry letters 05 2019 - 1215-1219 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2019.03.015 doi
Alcohols--chemistry
Amines--chemistry
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Proliferation
Cytotoxins--chemistry
Drug Screening Assays, Antitumor--methods
Floxuridine--chemistry
Humans
Indoles--chemistry
Molecular Structure
Prodrugs--chemical synthesis
Proof of Concept Study
Protein Kinase Inhibitors--chemical synthesis
Pyrroles--chemistry
Structure-Activity Relationship
Tumor Hypoxia