Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment.

Rolfo, Christian

Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment. [electronic resource] - Clinical pharmacokinetics 09 2019 - 1165-1174 p. digital

Publication Type: Clinical Trial, Phase II; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1179-1926

10.1007/s40262-019-00754-4 doi


Administration, Oral
Adult
Aged
Female
Humans
Kidney--physiopathology
Male
Metabolic Clearance Rate--drug effects
Middle Aged
Neoplasms--complications
No-Observed-Adverse-Effect Level
Phthalazines--administration & dosage
Piperazines--administration & dosage
Poly(ADP-ribose) Polymerase Inhibitors--administration & dosage
Renal Insufficiency--etiology
Safety