Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer's disease?

Fulop, Tamas

Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer's disease? [electronic resource] - Journal of neurovirology 10 2019 - 634-647 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

1538-2443

10.1007/s13365-019-00732-3 doi


AIDS Dementia Complex--etiology
Aged
Alzheimer Disease--etiology
Amyloid beta-Peptides--biosynthesis
Anti-HIV Agents--therapeutic use
Apoptosis
Astrocytes--virology
Bacterial Infections--complications
Brain--metabolism
Cytokines--metabolism
Endogenous Retroviruses--pathogenicity
HIV Infections--complications
HIV-1--physiology
Human Immunodeficiency Virus Proteins--physiology
Humans
Hydrogen-Ion Concentration
Lymphocytes--virology
Lysosomes--chemistry
Microglia--virology
Models, Neurological
Neurocognitive Disorders--etiology
Neurons--metabolism
Plaque, Amyloid
Virus Activation
Virus Diseases--complications