Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease.

Lesuisse, Dominique

Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease. [electronic resource] - Bioorganic & medicinal chemistry letters 04 2019 - 929-932 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2019.01.024 doi


Animals
Cell Line
Cricetinae
Drug Discovery
Gene Expression Regulation--drug effects
Homeodomain Proteins--metabolism
Interleukin-1beta--genetics
Mice
Microglia--drug effects
Molecular Structure
Neurons--drug effects
Neuroprotective Agents--chemical synthesis
Nuclear Receptor Subfamily 4, Group A, Member 2--genetics
Parkinson Disease--drug therapy
Rats
Retinoid X Receptors--genetics