Synthesis and structure-activity relationship of tyrosinase inhibiting novel bi-heterocyclic acetamides: Mechanistic insights through enzyme inhibition, kinetics and computational studies.

Butt, Abdul Rehman Sadiq

Synthesis and structure-activity relationship of tyrosinase inhibiting novel bi-heterocyclic acetamides: Mechanistic insights through enzyme inhibition, kinetics and computational studies. [electronic resource] - Bioorganic chemistry 05 2019 - 459-472 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2120

10.1016/j.bioorg.2019.01.036 doi


Acetamides--chemical synthesis
Agaricales--enzymology
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemical synthesis
Heterocyclic Compounds--chemical synthesis
Kinetics
Molecular Docking Simulation
Molecular Structure
Monophenol Monooxygenase--antagonists & inhibitors
Structure-Activity Relationship