A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring

Voss, Martin H

A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 05 2019 - 2699-2707 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-18-1959 doi


Adult
Aged
Benzimidazoles--pharmacokinetics
Drug Administration Schedule
Female
Follow-Up Studies
Gene Fusion
Humans
Male
Maximum Tolerated Dose
Middle Aged
Mutation
Neoplasms--drug therapy
Prognosis
Protein Kinase Inhibitors--pharmacokinetics
Pyrazoles--pharmacokinetics
Receptor, Fibroblast Growth Factor, Type 1--antagonists & inhibitors
Receptor, Fibroblast Growth Factor, Type 2--antagonists & inhibitors
Receptor, Fibroblast Growth Factor, Type 3--antagonists & inhibitors
Signal Transduction
Tissue Distribution