A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.

Ideno, Noboru

A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination. [electronic resource] - Laboratory investigation; a journal of technical methods and pathology Jul 2019 - 1233-1244 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1530-0307

10.1038/s41374-018-0171-z doi


Animals
CRISPR-Cas Systems--genetics
Dependovirus--genetics
Gene Editing--methods
Gene Transfer Techniques
Genetic Vectors--genetics
HEK293 Cells
Humans
Mice
Mice, Inbred C57BL
Mice, Transgenic
Neoplasms, Experimental
Pancreatic Neoplasms
RNA, Guide, CRISPR-Cas Systems--genetics
Recombination, Genetic--genetics