Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo.
Ma, Juan
Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo. [electronic resource] - Investigational new drugs 10 2019 - 1036-1043 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-0646
10.1007/s10637-018-00719-7 doi
Animals
Antibodies, Bispecific--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis
B7 Antigens--antagonists & inhibitors
CD3 Complex--antagonists & inhibitors
Cell Proliferation
Humans
In Vitro Techniques
Lymphocyte Activation
Melanoma--drug therapy
Mice
Mice, SCID
T-Lymphocytes--immunology
T-Lymphocytes, Cytotoxic--immunology
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo. [electronic resource] - Investigational new drugs 10 2019 - 1036-1043 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-0646
10.1007/s10637-018-00719-7 doi
Animals
Antibodies, Bispecific--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis
B7 Antigens--antagonists & inhibitors
CD3 Complex--antagonists & inhibitors
Cell Proliferation
Humans
In Vitro Techniques
Lymphocyte Activation
Melanoma--drug therapy
Mice
Mice, SCID
T-Lymphocytes--immunology
T-Lymphocytes, Cytotoxic--immunology
Tumor Cells, Cultured
Xenograft Model Antitumor Assays