Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1.
Chen, Wei
Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1. [electronic resource] - CNS neuroscience & therapeutics 06 2019 - 704-713 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1755-5949
10.1111/cns.13101 doi
Animals
Astrocytes--drug effects
Blood-Brain Barrier--drug effects
Calcium--metabolism
Cardiovascular Agents--pharmacology
Cell Hypoxia--drug effects
Cells, Cultured
Coculture Techniques
Endothelial Cells--drug effects
Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors
Mice
Microvessels--drug effects
Phosphorylation--drug effects
Propofol--pharmacology
Vascular Endothelial Growth Factor A--antagonists & inhibitors
Zonula Occludens-1 Protein--metabolism
Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1. [electronic resource] - CNS neuroscience & therapeutics 06 2019 - 704-713 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1755-5949
10.1111/cns.13101 doi
Animals
Astrocytes--drug effects
Blood-Brain Barrier--drug effects
Calcium--metabolism
Cardiovascular Agents--pharmacology
Cell Hypoxia--drug effects
Cells, Cultured
Coculture Techniques
Endothelial Cells--drug effects
Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors
Mice
Microvessels--drug effects
Phosphorylation--drug effects
Propofol--pharmacology
Vascular Endothelial Growth Factor A--antagonists & inhibitors
Zonula Occludens-1 Protein--metabolism