Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells.
Clemente-Soto, Aldo F
Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells. [electronic resource] - Molecular medicine reports Mar 2019 - 2097-2106 p. digital
Publication Type: Journal Article
1791-3004
10.3892/mmr.2019.9850 doi
Apoptosis--drug effects
Binding Sites
Female
G2 Phase Cell Cycle Checkpoints--drug effects
HeLa Cells
Humans
Molecular Docking Simulation
Multiprotein Complexes--chemistry
Oncogene Proteins, Viral--chemistry
Papillomavirus Infections--drug therapy
Protein Binding
Proto-Oncogene Proteins c-mdm2--chemistry
Quercetin--pharmacology
Repressor Proteins--chemistry
Tumor Suppressor Protein p53--chemistry
Ubiquitin-Protein Ligases--chemistry
Uterine Cervical Neoplasms--drug therapy
Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells. [electronic resource] - Molecular medicine reports Mar 2019 - 2097-2106 p. digital
Publication Type: Journal Article
1791-3004
10.3892/mmr.2019.9850 doi
Apoptosis--drug effects
Binding Sites
Female
G2 Phase Cell Cycle Checkpoints--drug effects
HeLa Cells
Humans
Molecular Docking Simulation
Multiprotein Complexes--chemistry
Oncogene Proteins, Viral--chemistry
Papillomavirus Infections--drug therapy
Protein Binding
Proto-Oncogene Proteins c-mdm2--chemistry
Quercetin--pharmacology
Repressor Proteins--chemistry
Tumor Suppressor Protein p53--chemistry
Ubiquitin-Protein Ligases--chemistry
Uterine Cervical Neoplasms--drug therapy