High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells.

Varghese, Sharon

High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells. [electronic resource] - Biomolecules 01 2019

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2218-273X

10.3390/biom9010016 doi


Adaptor Proteins, Signal Transducing--metabolism
Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Cycle Proteins
Cell Line, Tumor
Cell Proliferation--drug effects
Female
Glucose--pharmacology
Humans
Hypoglycemic Agents--pharmacology
Metformin--pharmacology
Phosphoproteins--metabolism
TOR Serine-Threonine Kinases--antagonists & inhibitors
Triple Negative Breast Neoplasms--metabolism