Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw.

Zhu, Weiwen

Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology 04 2019 - 5208-5219 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-6860

10.1096/fj.201801791RR doi


Animals
Bisphosphonate-Associated Osteonecrosis of the Jaw--drug therapy
Blotting, Western
Bone Density Conservation Agents--therapeutic use
Cells, Cultured
Flow Cytometry
Macrophage Activation--drug effects
Macrophages--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Microscopy, Confocal
Toll-Like Receptor 4--metabolism
Wound Healing--drug effects
X-Ray Microtomography
Zoledronic Acid--therapeutic use