Synthesis and structure-activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes: A small modification at tetrazole C5 markedly influences the in vivo antitumor efficacy.

Komeda, Seiji

Synthesis and structure-activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes: A small modification at tetrazole C5 markedly influences the in vivo antitumor efficacy. [electronic resource] - Journal of inorganic biochemistry 03 2019 - 82-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-3344

10.1016/j.jinorgbio.2018.12.009 doi


Animals
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cisplatin--chemistry
Colorectal Neoplasms--drug therapy
Drug Resistance, Neoplasm--drug effects
Mice
Mice, Inbred BALB C
Organoplatinum Compounds--chemical synthesis
Oxaliplatin--chemistry
Structure-Activity Relationship
Tetrazoles--chemistry