Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.

Pati, Maria Laura

Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability. [electronic resource] - European journal of medicinal chemistry Feb 2019 - 59-76 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2018.12.029 doi


Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Apoptosis--drug effects
Binding Sites
Bortezomib--therapeutic use
Cell Cycle--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Cyclooxygenase 1--chemistry
Cyclooxygenase 2--metabolism
Cyclooxygenase Inhibitors--chemistry
Humans
Isoxazoles--chemistry
Multiple Myeloma--drug therapy
Platelet Aggregation Inhibitors--pharmacology
Protein Binding
Structure-Activity Relationship