Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma.
Porcelli, L
Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma. [electronic resource] - Cancer letters 03 2019 - 1-10 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2018.12.013 doi
Antimitotic Agents--chemical synthesis
Biphenyl Compounds--chemical synthesis
CDC2 Protein Kinase--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Cyclin B1--metabolism
Gene Expression Regulation, Neoplastic--drug effects
Hodgkin Disease--drug therapy
Humans
Membrane Potential, Mitochondrial--drug effects
Mitochondria--drug effects
Molecular Structure
Nicotine--chemistry
Prometaphase--drug effects
Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma. [electronic resource] - Cancer letters 03 2019 - 1-10 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2018.12.013 doi
Antimitotic Agents--chemical synthesis
Biphenyl Compounds--chemical synthesis
CDC2 Protein Kinase--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Cyclin B1--metabolism
Gene Expression Regulation, Neoplastic--drug effects
Hodgkin Disease--drug therapy
Humans
Membrane Potential, Mitochondrial--drug effects
Mitochondria--drug effects
Molecular Structure
Nicotine--chemistry
Prometaphase--drug effects