Mechanical exposure and diacerein treatment modulates integrin-FAK-MAPKs mechanotransduction in human osteoarthritis chondrocytes.

Lohberger, Birgit

Mechanical exposure and diacerein treatment modulates integrin-FAK-MAPKs mechanotransduction in human osteoarthritis chondrocytes. [electronic resource] - Cellular signalling 04 2019 - 23-30 p. digital

Publication Type: Journal Article

1873-3913

10.1016/j.cellsig.2018.12.010 doi


ADAMTS Proteins--metabolism
Anthraquinones--pharmacology
Anti-Inflammatory Agents--pharmacology
Cell Line
Chondrocytes--pathology
Endopeptidases--metabolism
Focal Adhesion Kinase 1--metabolism
Humans
Interleukin-6--metabolism
Ion Channels--biosynthesis
Matrix Metalloproteinases--metabolism
Mechanotransduction, Cellular--physiology
Osteoarthritis--pathology
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Stress, Mechanical
Stress, Physiological--physiology
Thiolester Hydrolases--metabolism