Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid.

Kapoor, Garima

Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid. [electronic resource] - Bioorganic chemistry 03 2019 - 478-492 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2120

10.1016/j.bioorg.2018.12.004 doi


Animals
Binding Sites
Diabetes Mellitus, Experimental--chemically induced
Drug Design
Female
Glucose Tolerance Test
Half-Life
Humans
Hypoglycemic Agents--chemical synthesis
Male
Molecular Docking Simulation
Oleic Acid--chemistry
PPAR gamma--chemistry
Rats
Rats, Wistar
Schiff Bases--chemistry
Structure-Activity Relationship