A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells.

Lanoie, Delphine

A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells. [electronic resource] - Virology 02 2019 - 73-79 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1096-0341

10.1016/j.virol.2018.12.010 doi


Animals
Capsid Proteins--genetics
Cell Line
Chlorocebus aethiops
Codon, Initiator--genetics
Cricetinae
Genome, Viral
Interferons--pharmacology
Mice
Mutation
Orthoreovirus, Mammalian--drug effects
Reverse Genetics
Vero Cells
Virus Replication