In vitro proteomic analysis of methapyrilene toxicity in rat hepatocytes reveals effects on intermediary metabolism.

Braeuning, Albert

In vitro proteomic analysis of methapyrilene toxicity in rat hepatocytes reveals effects on intermediary metabolism. [electronic resource] - Archives of toxicology 02 2019 - 369-383 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-0738

10.1007/s00204-018-2360-3 doi


Animals
Cell Culture Techniques--methods
Chemical and Drug Induced Liver Injury--metabolism
Computational Biology
Gene Expression Profiling
Hepatocytes--drug effects
Histamine H1 Antagonists--toxicity
Male
Mass Spectrometry
Methapyrilene--toxicity
Proteins--genetics
Proteomics--methods
Rats, Wistar
Toxicity Tests--methods