Protective effects of selenium on acetaminophen-induced hepatotoxicity in the rat.
Schnell, R C
Protective effects of selenium on acetaminophen-induced hepatotoxicity in the rat. [electronic resource] - Toxicology and applied pharmacology Aug 1988 - 1-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0041-008X
10.1016/s0041-008x(88)80002-4 doi
Acetaminophen--antagonists & inhibitors
Alanine Transaminase--blood
Animals
Aspartate Aminotransferases--blood
Chemical and Drug Induced Liver Injury
Cytochrome P-450 Enzyme System--metabolism
Glucosephosphate Dehydrogenase--metabolism
Glutamate-Cysteine Ligase--metabolism
Glutathione--metabolism
Glutathione Transferase--metabolism
Liver--drug effects
Liver Diseases--prevention & control
Male
NADPH-Ferrihemoprotein Reductase--metabolism
Protein Binding--drug effects
Rats
Rats, Inbred Strains
Selenium--pharmacology
Protective effects of selenium on acetaminophen-induced hepatotoxicity in the rat. [electronic resource] - Toxicology and applied pharmacology Aug 1988 - 1-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0041-008X
10.1016/s0041-008x(88)80002-4 doi
Acetaminophen--antagonists & inhibitors
Alanine Transaminase--blood
Animals
Aspartate Aminotransferases--blood
Chemical and Drug Induced Liver Injury
Cytochrome P-450 Enzyme System--metabolism
Glucosephosphate Dehydrogenase--metabolism
Glutamate-Cysteine Ligase--metabolism
Glutathione--metabolism
Glutathione Transferase--metabolism
Liver--drug effects
Liver Diseases--prevention & control
Male
NADPH-Ferrihemoprotein Reductase--metabolism
Protein Binding--drug effects
Rats
Rats, Inbred Strains
Selenium--pharmacology