Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion.
Scarneo, Scott A
Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion. [electronic resource] - Scientific reports 11 2018 - 17058 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2045-2322
10.1038/s41598-018-35189-7 doi
Animals
Female
MAP Kinase Kinase Kinases--genetics
Macrophages--drug effects
Male
Mice
Mice, Inbred C57BL
Tumor Necrosis Factor-alpha--metabolism
Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion. [electronic resource] - Scientific reports 11 2018 - 17058 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2045-2322
10.1038/s41598-018-35189-7 doi
Animals
Female
MAP Kinase Kinase Kinases--genetics
Macrophages--drug effects
Male
Mice
Mice, Inbred C57BL
Tumor Necrosis Factor-alpha--metabolism