The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics.
Riley, Timothy P
The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics. [electronic resource] - Seminars in cell & developmental biology 12 2018 - 30-41 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review
1096-3634
10.1016/j.semcdb.2017.10.017 doi
Animals
Antibodies--genetics
Germ-Line Mutation--genetics
Humans
Immunotherapy
Protein Binding--genetics
Receptors, Antigen, T-Cell--genetics
Signal Transduction--genetics
T-Lymphocytes--drug effects
The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics. [electronic resource] - Seminars in cell & developmental biology 12 2018 - 30-41 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review
1096-3634
10.1016/j.semcdb.2017.10.017 doi
Animals
Antibodies--genetics
Germ-Line Mutation--genetics
Humans
Immunotherapy
Protein Binding--genetics
Receptors, Antigen, T-Cell--genetics
Signal Transduction--genetics
T-Lymphocytes--drug effects