Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma.

Scafoglio, Claudio R

Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma. [electronic resource] - Science translational medicine 11 2018

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1946-6242

10.1126/scitranslmed.aat5933 doi


Adenocarcinoma of Lung--diagnosis
Aged
Aged, 80 and over
Animals
Biological Transport--drug effects
Cell Differentiation
Cell Proliferation--drug effects
Female
Glucose--metabolism
Glucose Transporter Type 1--metabolism
Humans
Male
Mice, SCID
Mice, Transgenic
Middle Aged
Molecular Targeted Therapy
Neoplasm Staging
Positron-Emission Tomography
Precancerous Conditions--metabolism
Sodium-Glucose Transporter 2--metabolism
Sodium-Glucose Transporter 2 Inhibitors--pharmacology
Survival Analysis
Xenograft Model Antitumor Assays