Ambroxol attenuates cisplatin-induced hepatotoxicity and nephrotoxicity via inhibition of p-JNK/p-ERK.

Bishr, Abeer

Ambroxol attenuates cisplatin-induced hepatotoxicity and nephrotoxicity via inhibition of p-JNK/p-ERK. [electronic resource] - Canadian journal of physiology and pharmacology Jan 2019 - 55-64 p. digital

Publication Type: Journal Article

1205-7541

10.1139/cjpp-2018-0528 doi


Acute Kidney Injury--chemically induced
Ambroxol--therapeutic use
Animals
Antineoplastic Agents--toxicity
Chemical and Drug Induced Liver Injury--metabolism
Cisplatin--toxicity
Male
Oxidative Stress--drug effects
Rats
Rats, Wistar
Reactive Oxygen Species--metabolism