CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.

Pang, Paul D

CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. [electronic resource] - Journal of the American Heart Association 10 2018 - e010393 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2047-9980

10.1161/JAHA.118.010393 doi


Alleles
Animals
Arrhythmias, Cardiac
Clustered Regularly Interspaced Short Palindromic Repeats--genetics
Disease Models, Animal
Electrocardiography
Female
Gene Expression Regulation, Developmental
Heart Conduction System--metabolism
Male
Mice
Mice, Transgenic
NAV1.5 Voltage-Gated Sodium Channel--biosynthesis
Phenotype
Pregnancy
Pregnancy, Animal
RNA--genetics