Oxidation of the alcohol dehydrogenase inhibitor pyrazole to 4-hydroxypyrazole by microsomes. Effect of cytochrome P-450 inducing agents.

Feierman, D E

Oxidation of the alcohol dehydrogenase inhibitor pyrazole to 4-hydroxypyrazole by microsomes. Effect of cytochrome P-450 inducing agents. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals - 634-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0090-9556


Alcohol Dehydrogenase--antagonists & inhibitors
Animals
Chromatography, High Pressure Liquid
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction
Fomepizole
Male
Microsomes, Liver--drug effects
NAD--pharmacology
Oxidation-Reduction
Pyrazoles--metabolism
Rats
Rats, Inbred Strains