The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity.

Srinontong, Piyarat

The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity. [electronic resource] - Biochemical and biophysical research communications 11 2018 - 20-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2018.10.055 doi


Animals
B-Lymphocytes--immunology
Cytidine Deaminase--deficiency
Disease Resistance--genetics
Enzyme Activation
Female
Gene Expression Regulation
Genes, Reporter
Immune Sera--administration & dosage
Immunization, Passive--methods
Immunoglobulin mu-Chains--blood
Interferon-gamma--genetics
Leishmania donovani--immunology
Leishmaniasis, Visceral--genetics
Luciferases--genetics
Mice
Mice, Knockout
NADPH Oxidases--genetics
Parasite Load
Reactive Oxygen Species--immunology
Signal Transduction
Th1 Cells--immunology
AICDA (Activation-Induced Cytidine Deaminase)