KDM4B-regulated unfolded protein response as a therapeutic vulnerability in
Wang, Wenyu
KDM4B-regulated unfolded protein response as a therapeutic vulnerability in [electronic resource] - The Journal of experimental medicine 11 2018 - 2833-2849 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1540-9538
10.1084/jem.20180439 doi
Animals
Apoptosis--drug effects
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
Enzyme Inhibitors--pharmacology
Eukaryotic Initiation Factor-2--genetics
Female
Humans
Jumonji Domain-Containing Histone Demethylases--genetics
Mice
Mice, Inbred NOD
Mice, SCID
PTEN Phosphohydrolase--deficiency
Phosphatidylinositol 3-Kinases--genetics
Phosphoinositide-3 Kinase Inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Signal Transduction--drug effects
Triple Negative Breast Neoplasms--drug therapy
Unfolded Protein Response--drug effects
Xenograft Model Antitumor Assays
KDM4B-regulated unfolded protein response as a therapeutic vulnerability in [electronic resource] - The Journal of experimental medicine 11 2018 - 2833-2849 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1540-9538
10.1084/jem.20180439 doi
Animals
Apoptosis--drug effects
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
Enzyme Inhibitors--pharmacology
Eukaryotic Initiation Factor-2--genetics
Female
Humans
Jumonji Domain-Containing Histone Demethylases--genetics
Mice
Mice, Inbred NOD
Mice, SCID
PTEN Phosphohydrolase--deficiency
Phosphatidylinositol 3-Kinases--genetics
Phosphoinositide-3 Kinase Inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Signal Transduction--drug effects
Triple Negative Breast Neoplasms--drug therapy
Unfolded Protein Response--drug effects
Xenograft Model Antitumor Assays