Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors.
Amr, Abd El-Galil E
Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors. [electronic resource] - Molecules (Basel, Switzerland) Sep 2018
Publication Type: Journal Article
1420-3049
10.3390/molecules23102416 doi
Antineoplastic Agents--chemistry
Cell Proliferation--drug effects
Cyclin-Dependent Kinase 2--antagonists & inhibitors
Drug Screening Assays, Antitumor
Gene Expression Regulation, Neoplastic--drug effects
Hep G2 Cells
Humans
MCF-7 Cells
Macrocyclic Compounds--chemistry
Molecular Docking Simulation
Molecular Structure
Neoplasms--drug therapy
Peptides--chemistry
Protein Kinase Inhibitors--chemistry
Receptor, Platelet-Derived Growth Factor beta--antagonists & inhibitors
Structure-Activity Relationship
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors
Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors. [electronic resource] - Molecules (Basel, Switzerland) Sep 2018
Publication Type: Journal Article
1420-3049
10.3390/molecules23102416 doi
Antineoplastic Agents--chemistry
Cell Proliferation--drug effects
Cyclin-Dependent Kinase 2--antagonists & inhibitors
Drug Screening Assays, Antitumor
Gene Expression Regulation, Neoplastic--drug effects
Hep G2 Cells
Humans
MCF-7 Cells
Macrocyclic Compounds--chemistry
Molecular Docking Simulation
Molecular Structure
Neoplasms--drug therapy
Peptides--chemistry
Protein Kinase Inhibitors--chemistry
Receptor, Platelet-Derived Growth Factor beta--antagonists & inhibitors
Structure-Activity Relationship
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors