4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells.
Chavez Alvarez, Atziri Corin
4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells. [electronic resource] - Bioorganic & medicinal chemistry 10 2018 - 5045-5052 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2018.09.001 doi
Antimitotic Agents--chemical synthesis
Antineoplastic Agents--chemical synthesis
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Cells, Cultured
Cytochrome P-450 CYP1A1--metabolism
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Female
Humans
Molecular Structure
Prodrugs--chemical synthesis
Structure-Activity Relationship
4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells. [electronic resource] - Bioorganic & medicinal chemistry 10 2018 - 5045-5052 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2018.09.001 doi
Antimitotic Agents--chemical synthesis
Antineoplastic Agents--chemical synthesis
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Cells, Cultured
Cytochrome P-450 CYP1A1--metabolism
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Female
Humans
Molecular Structure
Prodrugs--chemical synthesis
Structure-Activity Relationship