Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan.

Singh, Tanu

Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan. [electronic resource] - Developmental cell 09 2018 - 720-734.e6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1878-1551

10.1016/j.devcel.2018.08.008 doi


Animals
Autophagy
Cell Proliferation
Drosophila Proteins--genetics
Drosophila melanogaster--drug effects
Female
Hedgehog Proteins--genetics
Hypoglycemic Agents--pharmacology
Insulin--pharmacology
Insulin-Like Growth Factor I--genetics
Male
Ovarian Follicle--cytology
Receptors, Cell Surface--genetics
Signal Transduction--drug effects
Smoothened Receptor--genetics
Stem Cell Niche--drug effects
Stem Cells--cytology