Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity.
Zhu, Jiayu
Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity. [electronic resource] - Toxicology and applied pharmacology 11 2018 - 1-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2018.09.004 doi
A549 Cells
Animals
Antineoplastic Agents--administration & dosage
Antineoplastic Agents, Alkylating--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--administration & dosage
Antioxidant Response Elements--drug effects
Carcinoma, Non-Small-Cell Lung--drug therapy
Diterpenes--administration & dosage
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm--drug effects
Epoxy Compounds--administration & dosage
Hep G2 Cells
Humans
Lung Neoplasms--drug therapy
Male
Mice
Mice, Inbred C57BL
NF-E2-Related Factor 2--antagonists & inhibitors
Phenanthrenes--administration & dosage
Treatment Outcome
Tumor Burden--drug effects
Xenograft Model Antitumor Assays--methods
Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity. [electronic resource] - Toxicology and applied pharmacology 11 2018 - 1-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2018.09.004 doi
A549 Cells
Animals
Antineoplastic Agents--administration & dosage
Antineoplastic Agents, Alkylating--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--administration & dosage
Antioxidant Response Elements--drug effects
Carcinoma, Non-Small-Cell Lung--drug therapy
Diterpenes--administration & dosage
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm--drug effects
Epoxy Compounds--administration & dosage
Hep G2 Cells
Humans
Lung Neoplasms--drug therapy
Male
Mice
Mice, Inbred C57BL
NF-E2-Related Factor 2--antagonists & inhibitors
Phenanthrenes--administration & dosage
Treatment Outcome
Tumor Burden--drug effects
Xenograft Model Antitumor Assays--methods