Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.

Mabe, Nathaniel W

Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer. [electronic resource] - The Journal of clinical investigation 10 2018 - 4413-4428 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI99481 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis Regulatory Proteins--biosynthesis
Breast Neoplasms--drug therapy
Cell Line, Tumor
Drug Resistance, Neoplasm
Enhancer of Zeste Homolog 2 Protein--genetics
Epithelial-Mesenchymal Transition
Female
Gene Expression Regulation, Neoplastic
Gene Silencing
Histone Deacetylase 1--genetics
Histone Deacetylase 2--genetics
Humans
Mice
Mice, Nude
Neoplasm Recurrence, Local--drug therapy
Nuclear Proteins--genetics
Tumor Suppressor Proteins--biosynthesis
Twist-Related Protein 1--genetics