Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis.

Mafanda, Euphrasie Kawila

Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis. [electronic resource] - Cytokine 12 2019 - 154501 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1096-0023

10.1016/j.cyto.2018.07.032 doi


Actins--genetics
Animals
Carbon Tetrachloride--toxicity
Chemokine CCL2--metabolism
Collagen Type I--genetics
Collagen Type I, alpha 1 Chain
Cytokines--metabolism
Gene Expression Regulation--genetics
Hepatocytes--metabolism
Inflammation--metabolism
Leukocytes--metabolism
Liver--cytology
Liver Cirrhosis--chemically induced
Lymphokines--genetics
Macrophages--metabolism
Matrix Metalloproteinase 2--genetics
Membrane Proteins--genetics
Mice
Mice, Knockout
Myofibroblasts--cytology
Platelet-Derived Growth Factor--genetics
Serum Albumin--genetics
Suppressor of Cytokine Signaling 1 Protein--genetics
Tissue Inhibitor of Metalloproteinase-1--genetics