GPR56 promotes proliferation of colorectal cancer cells and enhances metastasis via epithelial‑mesenchymal transition through PI3K/AKT signaling activation.

Ji, Bing

GPR56 promotes proliferation of colorectal cancer cells and enhances metastasis via epithelial‑mesenchymal transition through PI3K/AKT signaling activation. [electronic resource] - Oncology reports Oct 2018 - 1885-1896 p. digital

Publication Type: Journal Article

1791-2431

10.3892/or.2018.6582 doi


Aged
Animals
Apoptosis
Biomarkers, Tumor--genetics
Case-Control Studies
Cell Cycle
Cell Movement
Cell Proliferation
Colorectal Neoplasms--genetics
Epithelial-Mesenchymal Transition
Female
Follow-Up Studies
Gene Expression Regulation, Neoplastic
Humans
Lymphatic Metastasis
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Invasiveness
Phosphatidylinositol 3-Kinases--genetics
Prognosis
Proto-Oncogene Proteins c-akt--genetics
Receptors, G-Protein-Coupled--genetics
Signal Transduction
Survival Rate
Tumor Cells, Cultured
Xenograft Model Antitumor Assays