Targeted and synergistic therapy for hepatocellular carcinoma: monosaccharide modified lipid nanoparticles for the co-delivery of doxorubicin and sorafenib.

Duan, Wendu

Targeted and synergistic therapy for hepatocellular carcinoma: monosaccharide modified lipid nanoparticles for the co-delivery of doxorubicin and sorafenib. [electronic resource] - Drug design, development and therapy 2018 - 2149-2161 p. digital

Publication Type: Journal Article

1177-8881

10.2147/DDDT.S166402 doi


Animals
Antineoplastic Agents--administration & dosage
Carcinoma, Hepatocellular--drug therapy
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Doxorubicin--administration & dosage
Drug Carriers--chemistry
Drug Delivery Systems
Drug Screening Assays, Antitumor
Hep G2 Cells
Humans
Lipids--chemistry
Liver Neoplasms--drug therapy
Liver Neoplasms, Experimental--drug therapy
Mice
Mice, Inbred BALB C
Mice, Nude
Monosaccharides--chemistry
Nanoparticles--chemistry
Sorafenib--administration & dosage
Structure-Activity Relationship