Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities.

Knez, Damijan

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities. [electronic resource] - European journal of medicinal chemistry Aug 2018 - 598-617 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2018.07.033 doi


Alzheimer Disease--drug therapy
Amyloid beta-Peptides--metabolism
Antioxidants--chemistry
Butyrylcholinesterase--metabolism
Caco-2 Cells
Cell Line, Tumor
Cholinesterase Inhibitors--chemistry
Drug Design
Humans
Ligands
Models, Molecular
Neuroprotective Agents--chemistry
Piperidines--chemistry