Role of Interstitial Fluid Turnover on Target Suppression by Therapeutic Biologics Using a Minimal Physiologically Based Pharmacokinetic Model.

Li, Xiaobing

Role of Interstitial Fluid Turnover on Target Suppression by Therapeutic Biologics Using a Minimal Physiologically Based Pharmacokinetic Model. [electronic resource] - The Journal of pharmacology and experimental therapeutics 10 2018 - 1-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1521-0103

10.1124/jpet.118.250134 doi


Biological Products--metabolism
Extracellular Fluid--metabolism
Models, Biological
Molecular Targeted Therapy
Tissue Distribution
Tumor Necrosis Factor-alpha--metabolism